Plasma and cerebrospinal fluid leptin levels are maintained despite enhanced food intake in progesterone-treated rats.

@article{Grueso2001PlasmaAC,
  title={Plasma and cerebrospinal fluid leptin levels are maintained despite enhanced food intake in progesterone-treated rats.},
  author={E Grueso and Milagros Rocha and Marisa Puerta},
  journal={European journal of endocrinology},
  year={2001},
  volume={144 6},
  pages={659-65}
}
OBJECTIVES For adipostatic control, increases in food intake are followed by increased leptin levels that in turn reduce food intake. However, progesterone administration increases both food intake and body weight. The aim of this study was to analyze changes in the white adipose tissue-leptin system in rats with enhanced plasma levels of progesterone. METHODS Female Wistar rats received progesterone chronically by means of subcutaneous implants over 30 days. RESULTS They showed an… CONTINUE READING

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