Plasma and Urine Beta - Thromboglobulin Concentration in Patients With Deep Vein

Abstract

Plasma and urine beta-thromboglobulin (BTG) were measured in 52 patients with established deep vein thrombosis (DVT) and in 1 00 patients with clinically suspected DVT but with a negative venogram. Both plasma BTG (geometric mean 54; 95% range 12-239 ng/mI) and urine BTG (0.25; 0.03-3.1 ng/mI) were significantly elevated (p < 0.005) in patients with DVT compared to symptomatic patients with a negative venogram (plasma BTG 32. 9-112 ng/mI; urine BTG 0.12, 0.02-0.58 ng/mI). Sensitivity (35%) and specificity (80%) of the plasma BTG assay for the diagnosis of DVT were low. The urine BTG assay had a sensitivity of 37% but a specificity of 1 00%. There was a significant correlation between plasma and urine BTG (r = 0.68, p < 0.005). Serial BTG measurements were made in

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Cite this paper

@inproceedings{Han2005PlasmaAU, title={Plasma and Urine Beta - Thromboglobulin Concentration in Patients With Deep Vein}, author={Y Han and Alexander G. G. Turpie and R . D . Butt and A . Zielinsky}, year={2005} }