Plasma amyloid beta, apolipoprotein E, lacunar infarcts, and white matter lesions.

  title={Plasma amyloid beta, apolipoprotein E, lacunar infarcts, and white matter lesions.},
  author={Ewoud J van Dijk and Niels Dani{\"e}l Prins and Sarah E. Vermeer and Albert Hofman and Cornelia M van Duijn and Peter J Koudstaal and Monique M. B. Breteler},
  journal={Annals of neurology},
  volume={55 4},
Lacunar brain infarcts and cerebral white matter lesions are frequently observed on magnetic resonance imaging scans in elderly subjects. These lesions are also frequent in patient with cerebral amyloid angiopathy. We examined whether plasma amyloid beta peptide (Abeta) levels are associated with lacunar infarcts and white matter lesions in the general population, and whether the apolipoprotein E (APOE) genotype modifies these associations. We studied 1,077 participants within the population… CONTINUE READING
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