Plasma amyloid-β oligomers level is a biomarker for Alzheimer's disease diagnosis.

@article{Zhou2012PlasmaAO,
  title={Plasma amyloid-β oligomers level is a biomarker for Alzheimer's disease diagnosis.},
  author={Lixiong Zhou and Kwok - Hung Chan and Leung Wing Chu and Jason SC Kwan and You - Qiang Song and L H Chen and Philip Wl Ho and Oumei Cheng and Joanne M.W. Ho and Karen Siu-Ling. Lam},
  journal={Biochemical and biophysical research communications},
  year={2012},
  volume={423 4},
  pages={697-702}
}
Amyloid beta (Aβ), especially Aβ oligomers, is important in Alzheimer's disease (AD) pathogenesis. We studied plasma Aβ(40), Aβ(42), and Aβ oligomers levels in 44 AD patients and 22 non-demented controls. Cognitive functions were assessed by Chinese version of mini-mental state examination (MMSE), Abbreviated Metal Test (AMT), Alzheimer's Disease Assessment Scale Cognitive Subscale (ADAS-cog). Plasma Aβ monomers and oligomers levels were measured by ELISA. We found that the median plasma Aβ(40… CONTINUE READING

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