Plasma adiponectin and soluble leptin receptor and risk of colorectal cancer: a prospective study.

  title={Plasma adiponectin and soluble leptin receptor and risk of colorectal cancer: a prospective study.},
  author={Mingyang Song and Xuehong Zhang and Kana Wu and Shuji Ogino and Charles S. Fuchs and Edward L. Giovannucci and Andrew T. Chan},
  journal={Cancer prevention research},
  volume={6 9},
Adipokines are adipocyte-secreted hormones that may mediate the etiologic link between obesity and colorectal cancer; however, the evidence from large prospective studies is limited. We prospectively evaluated the association of plasma adiponectin and soluble leptin receptor (sOB-R) with colorectal cancer risk within the Nurses' Health Study (1990-2008) and the Health Professionals Follow-up Study (1994-2008) among 616 incident colorectal cancer cases and 1,205 controls selected using risk-set… CONTINUE READING


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