Plasma Resistin Is Associated With Single Nucleotide Polymorphisms of a Possible Resistin Receptor, the Decorin Gene, in the General Japanese Population

@inproceedings{Onuma2013PlasmaRI,
  title={Plasma Resistin Is Associated With Single Nucleotide Polymorphisms of a Possible Resistin Receptor, the Decorin Gene, in the General Japanese Population},
  author={Hiroshi Onuma and Yasuharu Tabara and Ryoichi Kawamura and Jun Ohashi and Wataru Nishida and Yasunori Takata and Masaaki Ochi and Tatsuya Nishimiya and Ryuichi Kawamoto and Katsuhiko Kohara and Tetsuro Miki and Haruhiko Osawa},
  booktitle={Diabetes},
  year={2013}
}
Resistin is an adipokine secreted from adipocytes in mice. We previously reported that a single nucleotide polymorphism (SNP) -420 (rs1862513) in the human resistin gene (RETN), is correlated with plasma resistin. Decorin is a multifunctional proteoglycan, and its isoform, lacking 14 amino acids from the N terminal region of mature core decorin, recently was identified as a resistin receptor in mice. To examine whether SNPs in the vicinity of the human decorin gene (DCN) are associated with… CONTINUE READING
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