Plasma Peak and Trough Gentamicin Concentrations in Hospitalized Horses Receiving Intravenously Administered Gentamicin

@inproceedings{Bauquier2015PlasmaPA,
  title={Plasma Peak and Trough Gentamicin Concentrations in Hospitalized Horses Receiving Intravenously Administered Gentamicin},
  author={J R Bauquier and Radisson Hotel Boston and R. Sweeney and P Wilkins and R. D. Nolen‐Walston},
  booktitle={Journal of veterinary internal medicine},
  year={2015}
}
BACKGROUND Gentamicin is an aminoglycoside antimicrobial commonly used in horses at 6.6 mg/kg IV once daily. Therapeutic drug monitoring (TDM) can confirm desired peak concentration is reached for common bacterial isolates, and detect toxicosis associated with high trough values. OBJECTIVES Determine the relationship between gentamicin dose and plasma concentration in hospitalized horses, and identify a starting dose range to achieve peaks > 32 μg/mL. ANIMALS Sixty-five horses (2002-2010… CONTINUE READING

Citations

Publications citing this paper.

References

Publications referenced by this paper.
Showing 1-10 of 35 references

Antimicrobial Therapy in Veterinary Medicine, 5th ed

PM Dowling
2013
View 2 Excerpts

Logistic Regression Using SAS: Theory and Application, 2nd ed

P. Allison
Cary, NC: SAS Institute, • 2012

Therapeutic drug monitoring and LC-MS/MS.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences • 2012

Pharmacologic principles

PM Dowling
Equine Internal Medicine, 3rd ed. Mayland Heights: Elsevier/Saunders; • 2010

Similar Papers

Loading similar papers…