Plasma MicroRNA-21 concentration may be a useful biomarker in glioblastoma patients.

@article{IlhanMutlu2012PlasmaMC,
  title={Plasma MicroRNA-21 concentration may be a useful biomarker in glioblastoma patients.},
  author={Ayseguel Ilhan-Mutlu and L. Winona Wagner and Adelheid Woehrer and Julia Furtner and Georg Widhalm and Christine Marosi and Matthias Preusser},
  journal={Cancer investigation},
  year={2012},
  volume={30 8},
  pages={615-21}
}
BACKGROUND MicroRNAs are proposed as plasma biomarkers in cancer. Glioblastoma is the most frequent primary brain tumor of adults. MicroRNA-21 was shown to induce glioblastoma growth. AIMS To evaluate the circulating microRNA-21 in glioblastoma patients. METHODS MicroRNA-21 copies in glioblastoma plasma (n = 10, before surgery and during/after concomitant chemoradiotherapy), control plasma (n = 10), and tissue samples were analyzed using RT-qPCR. RESULTS MicroRNA-21 in glioblastoma was… CONTINUE READING