Plasma Levels of Soluble Interleukin-2 Receptor α: Associations With Clinical Cardiovascular Events and Genome-Wide Association Scan.

@article{Durda2015PlasmaLO,
  title={Plasma Levels of Soluble Interleukin-2 Receptor α: Associations With Clinical Cardiovascular Events and Genome-Wide Association Scan.},
  author={Peter Durda and Jeremy A. Sabourin and Ethan M. Lange and Mike A. Nalls and Josyf C Mychaleckyj and Nancy Swords Jenny and Jin Li and Jeremy D. Walston and Tamara B. Harris and Bruce M. Psaty and William Valdar and Yongmei Liu and Mary Cushman and Alex P. Reiner and Russell P Tracy and Leslie A. Lange},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={2015},
  volume={35 10},
  pages={
          2246-53
        }
}
OBJECTIVE Interleukin (IL) -2 receptor subunit α regulates lymphocyte activation, which plays an important role in atherosclerosis. Associations between soluble IL-2Rα (sIL-2Rα) and cardiovascular disease (CVD) have not been widely studied and little is known about the genetic determinants of sIL-2Rα levels. APPROACH AND RESULTS We measured baseline levels of sIL-2Rα in 4408 European American (EA) and 766 African American (AA) adults from the Cardiovascular Health Study (CHS) and examined… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 11 REFERENCES

Principal components analysis corrects for stratification in genome - wide association studies

  • L PriceA, J PattersonN, M PlengeR, E WeinblattM, A ShadickN, D Reich
  • Nat Genet
  • 2006

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