Plasma IGFBP-2 levels predict clinical outcomes of patients with high-grade gliomas.

@article{Lin2009PlasmaIL,
  title={Plasma IGFBP-2 levels predict clinical outcomes of patients with high-grade gliomas.},
  author={Yi Lin and Tao Jiang and Kaijia Zhou and Li Xu and Baoshi Chen and Guilin Li and Xiaoguang Qiu and Tianzi Jiang and Wei Jun Zhang and Sonya Wei Song},
  journal={Neuro-oncology},
  year={2009},
  volume={11 5},
  pages={468-76}
}
Insulin-like growth factor binding protein 2 (IGFBP-2) is a malignancy-associated protein measurable in tumors and blood. Increased IGFBP-2 is associated with shortened survival of advanced glioma patients. Thus, we examined plasma IGFBP-2 levels in glioma patients and healthy controls to evaluate its value as a plasma biomarker for glioma. Plasma IGFBP-2 levels in 196 patients with newly diagnosed glioma and 55 healthy controls were analyzed using an IGFBP-2 ELISA kit. Blood was collected… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 37 references

Insulin-like growth factor binding protein 2 promotes glioma development and progression.

Proceedings of the National Academy of Sciences of the United States of America • 2007

Prognostic significance of co-overexpression of the eGFR/IGFBP-2/HIF-2A genes in astrocytomas

CA Scrideli, CG JrCarlotti, JF Mata
J Neurooncol • 2007

Insulin - like growth factor binding protein 2 is a marker for antiestrogen resistant human breast cancer cell lines but is not a major growth regulator

A Juncker-Jensen, Lykkesfeldt Ae, J Worm
Growth Horm IGF Res • 2006

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