Plasma IGFBP-2 levels predict clinical outcomes of patients with high-grade gliomas.

  title={Plasma IGFBP-2 levels predict clinical outcomes of patients with high-grade gliomas.},
  author={Yi Lin and Tao Jiang and Kaijia Zhou and Li Xu and Baoshi Chen and Guilin Li and Xiaoguang Qiu and Tianzi Jiang and Wei Jun Zhang and Sonya Wei Song},
  volume={11 5},
Insulin-like growth factor binding protein 2 (IGFBP-2) is a malignancy-associated protein measurable in tumors and blood. Increased IGFBP-2 is associated with shortened survival of advanced glioma patients. Thus, we examined plasma IGFBP-2 levels in glioma patients and healthy controls to evaluate its value as a plasma biomarker for glioma. Plasma IGFBP-2 levels in 196 patients with newly diagnosed glioma and 55 healthy controls were analyzed using an IGFBP-2 ELISA kit. Blood was collected… CONTINUE READING


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