Plasma Epstein-Barr virus DNA and residual disease after radiotherapy for undifferentiated nasopharyngeal carcinoma.

@article{Chan2002PlasmaEV,
  title={Plasma Epstein-Barr virus DNA and residual disease after radiotherapy for undifferentiated nasopharyngeal carcinoma.},
  author={Anthony Tak Cheung Chan and Yuk Ming Dennis Lo and Benny Zee and Lisa Yuen-Shan Chan and B B Ma and Sing-fai Leung and Frankie Mo and Maria Paola Lai and Stephen V Ho and Dolly Poon Wai Sin Huang and Philip James Johnson},
  journal={Journal of the National Cancer Institute},
  year={2002},
  volume={94 21},
  pages={1614-9}
}
BACKGROUND Epstein-Barr virus (EBV) DNA can be detected and quantified in the plasma of patients with EBV-related tumors, such as nasopharyngeal carcinoma (NPC). Although NPC at early stages can be cured by radical radiotherapy, there is a high recurrence rate in patients with advanced NPC. The pretreatment level of circulating EBV DNA is a prognostic factor for NPC, but the prognostic value of post-treatment EBV DNA has not been studied. We designed a prospective study in Hong Kong, China, to… CONTINUE READING
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