Plasma-Derived Polyreactive Secretory-Like IgA and IgM Opsonizing Salmonella enterica Typhimurium Reduces Invasion and Gut Tissue Inflammation through Agglutination

@inproceedings{Bioley2017PlasmaDerivedPS,
  title={Plasma-Derived Polyreactive Secretory-Like IgA and IgM Opsonizing Salmonella enterica Typhimurium Reduces Invasion and Gut Tissue Inflammation through Agglutination},
  author={Gilles Bioley and Justine Monnerat and Marius L{\"o}tscher and C{\'e}dric Vonarburg and Adrian W. Zuercher and Blaise Corth{\'e}sy},
  booktitle={Front. Immunol.},
  year={2017}
}
Due to the increasing emergence of antibiotic-resistant strains of enteropathogenic bacteria, development of alternative treatments to fight against gut infections is a major health issue. While vaccination requires that a proper combination of antigen, adjuvant, and delivery route is defined to elicit protective immunity at mucosae, oral delivery of directly active antibody preparations, referred to as passive immunization, sounds like a valuable alternative. Along the gut, the strategy… CONTINUE READING
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