Plasma Cytokine and Endotoxin Levels Correlate with Survival in Patients with the Sepsis Syndrome

@article{Casey1993PlasmaCA,
  title={Plasma Cytokine and Endotoxin Levels Correlate with Survival in Patients with the Sepsis Syndrome},
  author={Larry Casey and Robert A. Balk and Roger C. Bone},
  journal={Annals of Internal Medicine},
  year={1993},
  volume={119},
  pages={771-778}
}
Sepsis is the 13th leading cause of death in the United States. From 1979 through 1987, sepsis was included in the discharge diagnosis of 2 570 000 hospitalized patients. Furthermore, the incidence of sepsis continues to increase and, despite the use of modern antibiotics and supportive therapy, the mortality rate for patients with the sepsis syndrome remains high (40% to 60%) [1-3]. The cascade of events leading from bacterial infection to the development of organ failure and death are poorly… 
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