Plasma Concentrations of Brain-derived Neurotrophic Factor in Patients Undergoing Minor Surgery: A Randomized Controlled Trial

@article{Vutskits2007PlasmaCO,
  title={Plasma Concentrations of Brain-derived Neurotrophic Factor in Patients Undergoing Minor Surgery: A Randomized Controlled Trial},
  author={Laszlo Vutskits and Christopher Lysakowski and Christoph Czarnetzki and Benoit Jenny and J. -C Copin and Martin R. Tram{\`e}r},
  journal={Neurochemical Research},
  year={2007},
  volume={33},
  pages={1325-1331}
}
AbstractWe measured perioperative plasma concentrations of brain-derived neurotrophic factor (BDNF), a major mediator of synaptic plasticity in the central nervous system, in males, 30–65 years old, undergoing lumbar or cervical discotomy. Patients were randomly allocated to a general anesthetic with propofol induction and maintenance or with thiopental induction and isoflurane maintenance. BDNF plasma concentrations were measured before induction (baseline), 15 min after induction but before… CONTINUE READING
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