Plasma Circulating Cell-free Nuclear and Mitochondrial DNA as Potential Biomarkers in the Peripheral Blood of Breast Cancer Patients.

@article{Mahmoud2015PlasmaCC,
  title={Plasma Circulating Cell-free Nuclear and Mitochondrial DNA as Potential Biomarkers in the Peripheral Blood of Breast Cancer Patients.},
  author={Enas H. Mahmoud and Amal M. Fawzy and Omar K Ahmad and Amr Mohamed Ali},
  journal={Asian Pacific journal of cancer prevention : APJCP},
  year={2015},
  volume={16 18},
  pages={8299-305}
}
BACKGROUND In Egypt, breast cancer is estimated to be the most common cancer among females. It is also a leading cause of cancer-related mortality. Use of circulating cell-free DNA (ccf-DNA) as non-invasive biomarkers is a promising tool for diagnosis and follow-up of breast cancer (BC) patients. OBJECTIVE To assess the role of circulating cell free DNA (nuclear and mitochondrial) in diagnosing BC. MATERIALS AND METHODS Multiplex real time PCR was used to detect the level of ccf nuclear and… CONTINUE READING
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