Plasma 3-nitrotyrosine is elevated in premature infants who develop bronchopulmonary dysplasia.

@article{Banks1998Plasma3I,
  title={Plasma 3-nitrotyrosine is elevated in premature infants who develop bronchopulmonary dysplasia.},
  author={Brie Ann Banks and Harry Ischiropoulos and M A McClelland and Philip L. Ballard and Roberta A. Ballard},
  journal={Pediatrics},
  year={1998},
  volume={101 5},
  pages={870-4}
}
OBJECTIVE Premature infants are susceptible to bronchopulmonary dysplasia (BPD), a chronic lung disease of infancy that appears to be caused in part by oxidative stress from hyperoxia. To investigate the possible role of nitric oxide-derived oxidants such as peroxynitrite in the etiology of BPD, we measured levels of plasma 3-nitrotyrosine, which is produced by the reaction of peroxynitrite with proteins. PATIENTS AND METHODS Ten premature infants who developed BPD, defined as requiring… CONTINUE READING