Plasma 25-Hydroxyvitamin D and Risk of Breast Cancer in Women Followed over 20 Years.

@article{Eliassen2016Plasma2D,
  title={Plasma 25-Hydroxyvitamin D and Risk of Breast Cancer in Women Followed over 20 Years.},
  author={A Heather Eliassen and Erica T. Warner and Bernard A Rosner and Laura S. Collins and Andrew H. Beck and Liza M. Quintana and Rulla M. Tamimi and Susan E. Hankinson},
  journal={Cancer research},
  year={2016},
  volume={76 18},
  pages={
          5423-30
        }
}
Experimental evidence supports a protective role of 25-hydroxyvitamin D [25(OH)D] in breast carcinogenesis, but epidemiologic evidence is inconsistent. Whether plasma 25(OH)D interacts with breast tumor expression of vitamin D receptor (VDR) and retinoid X receptor-α (RXR) has not been investigated. We conducted a nested case-control study in the Nurses' Health Study, with 1,506 invasive breast cancer cases diagnosed after blood donation in 1989-1990, 417 of whom donated a second sample in 2000… CONTINUE READING

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