Plasma, salivary and urinary cortisol levels following physiological and stress doses of hydrocortisone in normal volunteers

@inproceedings{Jung2014PlasmaSA,
  title={Plasma, salivary and urinary cortisol levels following physiological and stress doses of hydrocortisone in normal volunteers},
  author={Caroline Jung and Santo Greco and Hanh H. Nguyen and Jui T Ho and John G. Lewis and David James Torpy and Warrick J Inder},
  booktitle={BMC endocrine disorders},
  year={2014}
}
BACKGROUND Glucocorticoid replacement is essential in patients with primary and secondary adrenal insufficiency, but many patients remain on higher than recommended dose regimens. There is no uniformly accepted method to monitor the dose in individual patients. We have compared cortisol concentrations in plasma, saliva and urine achieved following "physiological" and "stress" doses of hydrocortisone as potential methods for monitoring glucocorticoid replacement. METHODS Cortisol profiles were… CONTINUE READING
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