Plaque reduction, a sensitive test for eastern encephalitis antibody.

Abstract

Serologic surveys of vertebrates to determine rates of eastern encephalitis infection were made to discover the most likely disseminators of virus in nature. Of the techniques available, neutralization is the most specific, and antibody is known to persist for many years. This communication reports a fivefold increase in sensitivity of neutralizing-antibody detection by the application of a plaquereducing technique.

Cite this paper

@article{Daniels1961PlaqueRA, title={Plaque reduction, a sensitive test for eastern encephalitis antibody.}, author={Jonathan B Daniels and Julia Ratner and Shannon Brown}, journal={Science}, year={1961}, volume={133 3453}, pages={640-1} }