Plaque Rupture is a Determinant of Vascular Events in Carotid Artery Atherosclerotic Disease: Involvement of Matrix Metalloproteinases 2 and 9

@inproceedings{Heo2011PlaqueRI,
  title={Plaque Rupture is a Determinant of Vascular Events in Carotid Artery Atherosclerotic Disease: Involvement of Matrix Metalloproteinases 2 and 9},
  author={Sung Hyuk Heo and Chang-Hoon Cho and Hye Ok Kim and Yong Hwa Jo and Kyung- Sik Yoon and Ju Hie Lee and J M Park and Key Chung Park and Tae Beom Ahn and Kyung Cheon Chung and Sung-Sang Yoon and Dae-il Chang},
  booktitle={Journal of clinical neurology},
  year={2011}
}
BACKGROUND AND PURPOSE Unstable carotid atherosclerotic plaques are characterized by cap rupture, leading to thromboembolism and stroke. Matrix metalloproteinases (MMPs) have been implicated in the progression of atherosclerosis and plaque rupture. The aim of this study was to assess the relationship between the expressions of MMP-2 and MMP-9 and carotid plaque instability. METHODS Eighty atherosclerotic plaques were collected from 74 patients undergoing carotid endarterectomy. Clinical… CONTINUE READING
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