Plants as a source of butyrylcholinesterase variants designed for enhanced cocaine hydrolase activity.

@article{Larrimore2013PlantsAA,
  title={Plants as a source of butyrylcholinesterase variants designed for enhanced cocaine hydrolase activity.},
  author={Katherine E. Larrimore and Matthew Barcus and Latha Kannan and Yang Gao and Chang-Guo Zhan and Stephen Brimijoin and Tsafrir S Mor},
  journal={Chemico-biological interactions},
  year={2013},
  volume={203 1},
  pages={
          217-20
        }
}
Cocaine addiction affects millions of people with disastrous personal and social consequences. Cocaine is one of the most reinforcing of all drugs of abuse, and even those who undergo rehabilitation and experience long periods of abstinence have more than 80% chance of relapse. Yet there is no FDA-approved treatment to decrease the likelihood of relapse in rehabilitated addicts. Recent studies, however, have demonstrated a promising potential treatment option with the help of the serum enzyme… CONTINUE READING
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