Plantago major protective effects on antioxidant status after administration of 7,12-Dimethylbenz(a)anthracene in rats.

@article{Oto2011PlantagoMP,
  title={Plantago major protective effects on antioxidant status after administration of 7,12-Dimethylbenz(a)anthracene in rats.},
  author={G{\"o}khan Oto and Suat Ekin and Hulya Ozkan Ozdemir and Hakkı Y{\"u}cel Demir and Semih Yasar and Abdulkadir Levent and Ismet Berber and Bardia Kaki},
  journal={Asian Pacific journal of cancer prevention : APJCP},
  year={2011},
  volume={12 2},
  pages={
          531-5
        }
}
AIM The present study was designed to evaluate effects of Plantago major extract on oxidative status in Wistar albino rats administrated 7,12-dimethylbenz(a)anthracene (DMBA). METHODS Rats were divided into three equal groups of 6 animals each: Group 1 controls, group 2 treated with DMBA (100 mg/kg, single dose) and group 3 receiving the DMBA and the aqueous extract at 100 mg/kg/d for 60 days. RESULTS Significant decrease in catalase (P < 0.05), carbonic anhydrase (p ≤ 0.01), reduced… CONTINUE READING

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