Plant transducers of the endoplasmic reticulum unfolded protein response.

  title={Plant transducers of the endoplasmic reticulum unfolded protein response.},
  author={Yuji Iwata and Nozomu Koizumi},
  journal={Trends in plant science},
  volume={17 12},
The unfolded protein response (UPR) activates a set of genes to overcome accumulation of unfolded proteins in the endoplasmic reticulum (ER), a condition termed ER stress, and constitutes an essential part of ER protein quality control that ensures efficient maturation of secretory and membrane proteins in eukaryotes. Recent studies on Arabidopsis and rice identified the signaling pathway in which the ER membrane-localized ribonuclease IRE1 (inositol-requiring enzyme 1) catalyzes unconventional… CONTINUE READING
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