Plant stem cell maintenance involves direct transcriptional repression of differentiation program

@inproceedings{Yadav2013PlantSC,
  title={Plant stem cell maintenance involves direct transcriptional repression of differentiation program},
  author={Ram Kishor Yadav and Mariano M. Perales and Jeremy Gruel and Carolyn K Ohno and Marcus Heisler and Thomas Girke and Henrik J{\"o}nsson and G. Venugopala Reddy},
  booktitle={Molecular systems biology},
  year={2013}
}
In animal systems, master regulatory transcription factors (TFs) mediate stem cell maintenance through a direct transcriptional repression of differentiation promoting TFs. Whether similar mechanisms operate in plants is not known. In plants, shoot apical meristems serve as reservoirs of stem cells that provide cells for all above ground organs. WUSCHEL, a homeodomain TF produced in cells of the niche, migrates into adjacent cells where it specifies stem cells. Through high-resolution genomic… CONTINUE READING