Plant phenolics as inhibitors of mutational and precarcinogenic events.

Abstract

Initiation of chemical carcinogenesis involves the intracellular formation of a highly reactive electrophile that can attack many chemical nucleophiles in the cell, including DNA, a process that seems to be a central mechanism of initiation. Competing chemical nucleophiles in the cell, such as endogenous glutathione, can act as protecting or blocking agents… (More)

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Cite this paper

@article{Newmark1987PlantPA, title={Plant phenolics as inhibitors of mutational and precarcinogenic events.}, author={Harold L. Newmark}, journal={Canadian journal of physiology and pharmacology}, year={1987}, volume={65 3}, pages={461-6} }