Plant glutathione S-transferases: enzymes with multiple functions in sickness and in health.

@article{Edwards2000PlantGS,
  title={Plant glutathione S-transferases: enzymes with multiple functions in sickness and in health.},
  author={Robert E Edwards and David P. Dixon and Virginia Walbot},
  journal={Trends in plant science},
  year={2000},
  volume={5 5},
  pages={193-8}
}
Glutathione S-transferases (GSTs) are abundant proteins encoded by a highly divergent, ancient gene family. Soluble GSTs form dimers, each subunit of which contains active sites that bind glutathione and hydrophobic ligands. Plant GSTs attach glutathione to electrophilic xenobiotics, which tags them for vacuolar sequestration. The role of GSTs in metabolism is unclear, although their complex regulation by environmental stimuli implies that they have important protective functions. Recent… CONTINUE READING
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