Plant extracts: initial screening, identification of bioactive compounds and effect against Candida albicans biofilms.

@article{Brighenti2017PlantEI,
  title={Plant extracts: initial screening, identification of bioactive compounds and effect against Candida albicans biofilms.},
  author={Fernanda Lourenç{\~a}o Brighenti and Marcos Salvador and Aline Vidal Lacerda Gontijo and Alberto Carlos Botazzo Delbem and {\'A}dina Cl{\'e}ia Botazzo Delbem and Cristina Soares and Maria Alcion{\'e}iac Carvalho de Oliveira and Camila Miorelli Girondi and Cristiane Yumi Koga-Ito},
  journal={Future microbiology},
  year={2017},
  volume={12},
  pages={15-27}
}
AIM This study screened plants from Brazilian Pantanal for Candida albicans antibiofilm activity. MATERIAL & METHODS Sixty extracts were obtained from ten plants using different extraction methods. Antifungal activity was assessed. Effects on biofilm inhibition and disruption and cytotoxicity were also evaluated. The most active extract was chemically characterized. RESULTS Buchenavia tomentosa ethanolic extract showed noticeable antifungal activity and was selected for biofilm experiments… CONTINUE READING