Plant-derived protease inhibitors LC-pi (Lavatera cashmeriana) inhibit human lung cancer cell proliferation in vitro.

@article{Rakashanda2015PlantderivedPI,
  title={Plant-derived protease inhibitors LC-pi (Lavatera cashmeriana) inhibit human lung cancer cell proliferation in vitro.},
  author={Syed Rakashanda and Asif Khurshid Qazi and Rabiya Majeed and Syed Mubashir Andrabi and Abid Hamid and Parduman Raj Sharma and S. Amin},
  journal={Nutrition and cancer},
  year={2015},
  volume={67 1},
  pages={156-66}
}
The objective of this study was to check the anticancer activity of purified protease inhibitors of Lavatera cashmeriana viz LC-pi I, II, III, and IV (Lavatera cashmeriana protease inhibitors) on A549 (lung) cell. It was found that LC-pi I and II significantly inhibited the proliferation of A549 cells with IC₅₀ value of 54 μg/ml and 38 μg/ml, respectively… CONTINUE READING