Plant defense responses in opium poppy cell cultures revealed by liquid chromatography-tandem mass spectrometry proteomics.

@article{Zulak2009PlantDR,
  title={Plant defense responses in opium poppy cell cultures revealed by liquid chromatography-tandem mass spectrometry proteomics.},
  author={Katherine G. Zulak and M. Farhanullah Khan and Joenel Alcantara and David C. Schriemer and Peter J Facchini},
  journal={Molecular & cellular proteomics : MCP},
  year={2009},
  volume={8 1},
  pages={86-98}
}
Opium poppy (Papaver somniferum) produces a diverse array of bioactive benzylisoquinoline alkaloids, including the narcotic analgesic morphine and the antimicrobial agent sanguinarine. In contrast to the plant, cell cultures of opium poppy do not accumulate alkaloids constitutively but produce sanguinarine in response to treatment with certain fungal-derived elicitors. The induction of sanguinarine biosynthesis provides a model platform to characterize the regulation of benzylisoquinoline… CONTINUE READING
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