Plant antimutagenic agents, 7. Structure and antimutagenic properties of cymobarbatol and 4-isocymobarbatol, new cymopols from green alga (Cymopolia barbata).

@article{Wall1989PlantAA,
  title={Plant antimutagenic agents, 7. Structure and antimutagenic properties of cymobarbatol and 4-isocymobarbatol, new cymopols from green alga (Cymopolia barbata).},
  author={Monroe E. Wall and Mansukh C. Wani and G Manikumar and Henry Taylor and Terence J. Hughes and K Gaetano and H W Gerwick and A T Mcphail and D. S. McPhail},
  journal={Journal of natural products},
  year={1989},
  volume={52 5},
  pages={1092-9}
}
Two new compounds, cymobarbatol and 4-isocymobarbatol, were isolated from the marine alga Cymopolia barbata. The complete structures and absolute stereochemistries of these compounds were elucidated by a variety of spectroscopic techniques and X-ray crystallography. Both compounds were found to be nontoxic over a broad concentration range to Salmonella typhimurium strains T-98 and T-100. Both compounds exhibited strong inhibition of the mutagenicity of 2-aminoanthracene and ethyl… CONTINUE READING

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