Plant antimutagenic agents, 3. Coumarins.

  title={Plant antimutagenic agents, 3. Coumarins.},
  author={M. Wall and M. Wani and G. Manikumar and T. Hughes and H. Taylor and R. McGivney and J. Warner},
  journal={Journal of natural products},
  volume={51 6},
Several coumarins were isolated from crude plant extracts by means of an antimutagenic assay procedure. These coumarins included psoralen from Psoralea corylifolia and imperatorin and osthol from Selinum monniere. Studies of structure-activity relationships of these and several other available coumarins were carried out with four mutagens. All of the coumarins were nontoxic and in particular showed high activity in the inhibition of the mutagenicity of benzo[a]pyrene. 
Antimutagenic agents from natural products of terrestrial and marine origin.
Effect of apigeninidin on the growth of selected bacteria
Inhibition of the mutagenicity of 2-nitrofluorene, 3-nitrofluoranthene and 1-nitropyrene by flavonoids, coumarins, quinones and other phenolic compounds.
  • R. Edenharder, X. Tang
  • Chemistry, Medicine
  • Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 1997
Copaifera multijuga oleoresin and its constituent diterpene (-)-copalic acid: Genotoxicity and chemoprevention study.