Plant adaptogens increase lifespan and stress resistance in C. elegans

  title={Plant adaptogens increase lifespan and stress resistance in C. elegans},
  author={Fred A. C. Wiegant and Silvia Surinova and E. Ytsma and Miriam Langelaar-Makkinje and Georg Wikman and Jan Andries Post},
Extracts of plant adaptogens such as Eleutherococcus senticosus (or Acanthopanax senticosus) and Rhodiola rosea can increase stress resistance in several model systems. We now show that both extracts also increase the mean lifespan of the nematode C. elegans in a dose-dependent way. In at least four independent experiments, 250 μg/ml Eleutherococcus (SHE-3) and 10–25 μg/ml Rhodiola (SHR-5) significantly increased life span between 10 and 20% (P < 0.001), increased the maximum lifespan with 2–3… CONTINUE READING
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