Plant NB-LRR proteins: tightly regulated sensors in a complex manner.

  title={Plant NB-LRR proteins: tightly regulated sensors in a complex manner.},
  author={Hyun-ah Lee and Seon-In Yeom},
  journal={Briefings in functional genomics},
  volume={14 4},
As plants are sessile, they have evolved hundreds of resistance (R) genes to defend themselves against multiple pathogens. Most of plant R genes encode proteins with the nucleotide-binding and leucine-rich repeat (NB-LRR) domains that interact with pathogen effectors to induce defense responses. Recent findings describing R proteins structures, host interactors and transcriptional and posttranscriptional regulators have broadened our understanding of R gene activity regulation. Genome-wide… CONTINUE READING
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