Plant Insecticide L-Canavanine Repels Drosophila via the Insect Orphan GPCR DmX

  title={Plant Insecticide L-Canavanine Repels Drosophila via the Insect Orphan GPCR DmX},
  author={Christian Mitri and Laurent Soustelle and Bérénice Framery and Jo{\"e}l Bockaert and M L Parmentier and Yves Grau},
  journal={PLoS Biology},
For all animals, the taste sense is crucial to detect and avoid ingesting toxic molecules. Many toxins are synthesized by plants as a defense mechanism against insect predation. One example of such a natural toxic molecule is L-canavanine, a nonprotein amino acid found in the seeds of many legumes. Whether and how insects are informed that some plants contain L-canavanine remains to be elucidated. In insects, the taste sense relies on gustatory receptors forming the gustatory receptor (Gr… 

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  • G. Rosenthal, D. Dahlman
  • Biology
    Proceedings of the National Academy of Sciences of the United States of America
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