Plant‐produced Zika virus envelope protein elicits neutralizing immune responses that correlate with protective immunity against Zika virus in mice

@inproceedings{Yang2018PlantproducedZV,
  title={Plant‐produced Zika virus envelope protein elicits neutralizing immune responses that correlate with protective immunity against Zika virus in mice},
  author={Ming Yang and Haiyan Sun and Huafang Lai and Jonathan Hurtado and Qiang Chen},
  booktitle={Plant biotechnology journal},
  year={2018}
}
The global Zika virus (ZIKV) outbreak and its link to foetal and newborn microcephaly and severe neurological complications in adults call for the urgent development of ZIKV vaccines. In response, we developed a subunit vaccine based on the ZIKV envelope (E) protein and investigated its immunogenicity in mice. Transient expression of ZIKV E (zE) resulted in… CONTINUE READING