Planktonic replication is essential for biofilm formation by Legionella pneumophila in a complex medium under static and dynamic flow conditions.

@article{Mampel2006PlanktonicRI,
  title={Planktonic replication is essential for biofilm formation by Legionella pneumophila in a complex medium under static and dynamic flow conditions.},
  author={J{\"o}rg Mampel and Thomas Spirig and Stefan S. Weber and Janus Haagensen and Soeren Molin and Hubert Hilbi},
  journal={Applied and environmental microbiology},
  year={2006},
  volume={72 4},
  pages={2885-95}
}
Legionella pneumophila persists for a long time in aquatic habitats, where the bacteria associate with biofilms and replicate within protozoan predators. While L. pneumophila serves as a paradigm for intracellular growth within protozoa, it is less clear whether the bacteria form or replicate within biofilms in the absence of protozoa. In this study, we analyzed surface adherence of and biofilm formation by L. pneumophila in a rich medium that supported axenic replication. Biofilm formation by… CONTINUE READING