Planejamento racional de fármacos baseado em produtos naturais

@inproceedings{Montanari2001PlanejamentoRD,
  title={Planejamento racional de f{\'a}rmacos baseado em produtos naturais},
  author={Carlos A. Montanari and Vanderlan da Silva Bolzani},
  year={2001}
}
In the area of drug discovery, natural products represent a myriad of templates for new lead discovery. It is, however, most unlikely that the bioactive principle itself shall become a drug; it is much more likely that a medicinal chemistry project needs to be initiated as soon the potency or selectivity or specificity of the new natural product candidate has been disclosed. Brazil has an enormous biodiversity where just a few has been disclosed. Nevertheless, it urges to initiate a joint… CONTINUE READING

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