Planarity of benzoyldithiocarbazate tuberculostatics. II. Diesters of benzoyldithiocarbazic acid.

@article{Szczesio2016PlanarityOB,
  title={Planarity of benzoyldithiocarbazate tuberculostatics. II. Diesters of benzoyldithiocarbazic acid.},
  author={Małgorzata Szczesio and Andrzej Olczak and Katarzyna Gobis and Ida Mazerant and Sylwia Kałużyńska and Henryk Foks and Marek L. Gł{\'o}wka},
  journal={Acta crystallographica. Section C, Structural chemistry},
  year={2016},
  volume={72 Pt 1},
  pages={75-9}
}
The emergence of drug-resistant strains of Mycobacterium tuberculosis has intensified efforts to identify new lead tuberculostatics. Our earlier studies concluded that the planarity of a molecule correlates well with its tuberculostatic activity. According to our hypothesis, only derivatives whose molecules are capable of adopting a planar conformation may… CONTINUE READING