Planar stacking interactions of arginine and aromatic side-chains in proteins.

@article{Flocco1994PlanarSI,
  title={Planar stacking interactions of arginine and aromatic side-chains in proteins.},
  author={Maria M. Flocco and Sherry L Mowbray},
  journal={Journal of molecular biology},
  year={1994},
  volume={235 2},
  pages={709-17}
}
A parallel stacking arrangement of the guanidinium groups of arginines directly over the center of the rings of aromatic side-chains is observed much more frequently in proteins than would be expected by chance. This type of interaction, which is often found in locations critical to the function, apparently serves to orient the arginine side-chain without interfering with its ability to form hydrogen bonds elsewhere. It is distinct from the interactions which involve the side-chains of… CONTINUE READING

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