Planar polarization of the denticle field in the Drosophila embryo: roles for Myosin II (zipper) and fringe.

@article{Walters2006PlanarPO,
  title={Planar polarization of the denticle field in the Drosophila embryo: roles for Myosin II (zipper) and fringe.},
  author={James W Walters and Stacie A Dilks and Stephen Dinardo},
  journal={Developmental biology},
  year={2006},
  volume={297 2},
  pages={323-39}
}
Epithelial planar cell polarity (PCP) allows epithelial cells to coordinate their development to that of the tissue in which they reside. The mechanisms that impart PCP as well as effectors that execute the polarizing instructions are being sought in many tissues. We report that the epidermal epithelium of Drosophila embryos exhibits PCP. Cells of the prospective denticle field, but not the adjacent smooth field, align precisely. This requires Myosin II (zipper) function, and we find that… CONTINUE READING

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