Planar cell polarity cadherin Celsr1 regulates skin hair patterning in the mouse.

@article{Ravni2009PlanarCP,
  title={Planar cell polarity cadherin Celsr1 regulates skin hair patterning in the mouse.},
  author={Aur{\'e}lia Ravni and Yibo Qu and Andre M Goffinet and Fadel Tissir},
  journal={The Journal of investigative dermatology},
  year={2009},
  volume={129 10},
  pages={2507-9}
}
TO THE EDITOR Skin hairs develop in a highly coordinated manner, and a complex genetic program controls their size, texture, density, and patterns (Schmidt-Ullrich and Paus, 2005; Sick et al., 2006; Schlake, 2007). In addition to their physical features, hairs are distributed in macroscopic patterns. In rodents, all body hairs are oriented caudally and those on the feet are pointed distally. Here, we report that hair patterning on the body and legs in mice are disturbed by targeted inactivation… CONTINUE READING

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