Plague immunization. I. Past and present trends.

@article{Meyer1974PlagueII,
  title={Plague immunization. I. Past and present trends.},
  author={K. F. Meyer and D. Cavanaugh and P. Bartelloni and J. Marshall},
  journal={The Journal of infectious diseases},
  year={1974},
  volume={129},
  pages={
          Suppl:S13-8
        }
}
Due to the erroneous concept relating reactogenicity to immunogenicity, killed plague vaccines were initially produced and standardized to insure that the majority of persons receiving them would experience severe local and systemic reactions. Subsequent studies have resulted in the production of relatively nontoxic, killed plague vaccines. Throughout the world the use of highly immunogenic, living, attenuated plague vaccines has resulted in frequent adverse local and systemic reactions… Expand
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