Placing ancient DNA sequences into reference phylogenies

  title={Placing ancient DNA sequences into reference phylogenies},
  author={Rui Martiniano and Bianca De Sanctis and Pille Hallast and Richard Durbin},
During the last decade, large volumes of ancient DNA (aDNA) data have been generated as part of whole-genome shotgun and target capture sequencing studies. This includes sequences from non-recombining loci such as the mitochondrial or Y chromosomes. However, given the highly degraded nature of aDNA data, post-mortem deamination and often low genomic coverage, combining ancient and modern samples for phylogenetic analyses remains difficult. Without care, these factors can lead to incorrect… 
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