Placental villous hypermaturation is associated with idiopathic preterm birth.

@article{Morgan2013PlacentalVH,
  title={Placental villous hypermaturation is associated with idiopathic preterm birth.},
  author={Terry K. Morgan and Jorge E. Tolosa and Lisa Mele and Ronald J. Wapner and Catherine Y. Spong and Yoram Sorokin and Donald J. Dudley and Alan M. Peaceman and Brian M. Mercer and John M Thorp and Mary Jo O'sullivan and Susan M. Ramin and Dwight J. Rouse and Bahaeddine M Sibai},
  journal={The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians},
  year={2013},
  volume={26 7},
  pages={
          647-53
        }
}
OBJECTIVE Pregnancy complications such as intra-amniotic infection, preeclampsia, and fetal intrauterine growth restriction (IUGR) account for most cases of preterm birth (PTB), but many spontaneous PTB cases do not have a clear etiology. We hypothesize that placental insufficiency may be a potential cause of idiopathic PTB. METHODS Secondary analysis of 82 placental samples from women with PTB obtained from a multicenter trial of repeat versus single antenatal corticosteroids. Samples were… CONTINUE READING
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