Placental vasculature in health and disease.

  title={Placental vasculature in health and disease.},
  author={Eliyahu V. Khankin and Caroline Royle and Siddharth Karumanchi},
  journal={Seminars in thrombosis and hemostasis},
  volume={36 3},
Both angiogenesis and vasculogenesis occur during normal placental development. Additionally, the placenta undergoes a process of vascular mimicry (also referred to as pseudo-vasculogenesis) where the placental cytotrophoblasts that invade the spiral arteries convert from an epithelial to an endothelial phenotype during normal pregnancy. Failure of placental angiogenesis and pseudo-vasculogenesis during placental development has been linked to the pathogenesis of preeclampsia and related… CONTINUE READING
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