Placental steroidogenesis in pregnant women with polycystic ovary syndrome.

  title={Placental steroidogenesis in pregnant women with polycystic ovary syndrome.},
  author={Manuel A Maliqueo and Hern{\'a}n E. Lara and Fernando S{\'a}nchez and B{\'a}rbara Echibur{\'u} and Nicolas M. Crisosto and Teresa Sir-Petermann},
  journal={European journal of obstetrics, gynecology, and reproductive biology},
  volume={166 2},
OBJECTIVE To evaluate the placental activity of steroid sulfatase (STS), 3β-hydroxysteroid dehydrogenase type 1 (3β-HSD-1) and P450 aromatase (P450arom) in polycystic ovarian syndrome (PCOS) compared to normal pregnant women. DESIGN Twenty pregnant women with PCOS and 30 control pregnant women who delivered at term were studied. Samples of placental tissue and cord blood were obtained after delivery. A maternal blood sample was obtained during the 34th week of gestation. In placental tissue… CONTINUE READING


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