Placental mesenchymal dysplasia: a case of a normal-appearing fetus with intrauterine growth restriction.

Abstract

In this paper, we described a placenta with vesicular lesions in a 23-year-old woman (1-gravid) who visited our hospital at 13 weeks of gestation on prenatal routine examination. Ultrasound findings showed multiple vesicular lesions which gradually increased as the pregnancy advanced, and a live normal-appearing fetus which was confirmed of IUGR at 30 weeks of gestation in her uterus. Throughout gestation, the maternal serum β-human chorionic gonadotropin level keeps normal, but the serum alpha-fetoprotein was higher than average. The patient delivered an 1800-g female without obvious anomalies at 35 weeks 5 days of gestation due to premature rupture of membrane. The diagnosis of placental mesenchymal dysplasia was determined on the pathological examination and androgenetic/biparental mosaicism in the placenta was identified by immunohistochemical staining of p57kip2.

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Cite this paper

@article{Li2014PlacentalMD, title={Placental mesenchymal dysplasia: a case of a normal-appearing fetus with intrauterine growth restriction.}, author={Hui Li and Lei Li and Xiao Tang and Fan Yang and Kai-xuan Yang}, journal={International journal of clinical and experimental pathology}, year={2014}, volume={7 8}, pages={5302-7} }