Placental insufficiency: programming of leptin secretion, blood pressure, and postnatal growth in two generations of Sprague-Dawley rats.

@article{Anderson2009PlacentalIP,
  title={Placental insufficiency: programming of leptin secretion, blood pressure, and postnatal growth in two generations of Sprague-Dawley rats.},
  author={Cindy Miller Anderson and F. L{\'o}pez L{\'o}pez and Ashley Sandeen and LuAnn K Johnson},
  journal={Biological research for nursing},
  year={2009},
  volume={10 3},
  pages={284-91}
}
Regulatory process may be altered in response to the intrauterine environment, leading to the development of altered growth trajectory and disease later in life. Previously, our lab reported reduced leptin levels in pregnant hypertensive Sprague-Dawley rat dams with placental insufficiency. The purposes of this study were to investigate the relationship between leptin levels, growth and hypertension in two generations of offspring exposed to placental insufficiency. Leptin levels were… CONTINUE READING