Placental inflammation and viral infection are implicated in second trimester pregnancy loss.

@article{Srinivas2006PlacentalIA,
  title={Placental inflammation and viral infection are implicated in second trimester pregnancy loss.},
  author={Sindhu K. Srinivas and Yujie Ma and Mary D. Sammel and Doris Chou and C Mcgrath and Samuel Parry and Michal A Elovitz},
  journal={American journal of obstetrics and gynecology},
  year={2006},
  volume={195 3},
  pages={797-802}
}
OBJECTIVE Second trimester pregnancy loss continues to be a poorly understood adverse obstetric outcome. A case control study was performed to determine if: (1) similar to early spontaneous preterm birth, second trimester loss is associated with histologic chorioamnionitis (HCA); and (2) if HCA is present, which organisms may mediate this placental inflammation. STUDY DESIGN Cases were patients with a spontaneous second trimester loss. Controls were patients who presented for induction of… CONTINUE READING