Placental Up-Regulation of Leptin and ARMS2 is Associated with Growth Discordance in Monochorionic Diamniotic Twin Pregnancies.

@article{Sun2017PlacentalUO,
  title={Placental Up-Regulation of Leptin and ARMS2 is Associated with Growth Discordance in Monochorionic Diamniotic Twin Pregnancies.},
  author={Luming Sun and Jia Zhou and Kai Wang and Jian Wang and Ling Ling Shang and Jianguang Zhang and Junqing Wu and David S Cram},
  journal={Twin research and human genetics : the official journal of the International Society for Twin Studies},
  year={2017},
  volume={20 2},
  pages={
          169-179
        }
}
Fetal growth discordance is a relatively common complication of monochorionic diamniotic (MCDA) twin pregnancies and is caused by a combination of maternal and placental factors. The aim of the study was to survey placental gene expression patterns and identify genes associated with growth discordance. Clinical samples comprised eight growth-discordant MCDA twin placentas (31+3-34+4 weeks gestational age) and six growth-concordant twin placentas (31+2-37 weeks gestational age). Gene expression… CONTINUE READING

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